Dr John Miklavcic

Assistant Professor

Schmid College of Science and Technology; Food Science; School of Pharmacy

Office Location: Keck Center for Science and Engineering 255

Phone: (714) 516-5520

Email: miklavcic@chapman.edu

Scholarly Works:: Google Scholar

Education:: University of Guelph, Bachelor of Science
University of Alberta, Master of Science
University of Alberta, Ph.D.

Biography

Research Interests

Dr. Miklavcic has a translational research program in human nutrition that focuses on understanding the therapeutic applications of functional foods and nutraceuticals in human health. He is particularly interested in how dietary lipids interact with and regulate gene function in neonatal health & development and in chronic conditions. Dr. Miklavcic uses quantitative and qualitative methods as well as applied and implementation research in studies with clinical populations of infants, adolescents and older adults.

Recent Creative, Scholarly Work and Publications: “Homogenization and thermal processing reduce the concentration of extracellular vesicles in bovine milk.” Colella A, Prakash A, Miklavcic JJ. Food Science & Nutrition. 2024;12: 131-140. DOI: 10.1002.fsn3.3749.; “Histopathology imaging and clinical data including remission status in pediatric inflammatory bowel disease patients.” Martin-King C, Nael A, Ehwerhemuepha L, Calvo B, Gates Q, Janchoi J, Ornelas E, Perez M, Venderby A, Miklavcic JJ, Grant K. Nature Scientific Data. 2024; 11: 761. DOI: 10.1038/s41597-024-03592-7.; “Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: a genetic association study.” Miklavcic JJ, Paterson N, Hahn-Holbrook J, Glynn L. Journal of Parenteral and Enteral Nutrition. 2024; 48(4): 479-485. DOI: 10.1002/jpen.2628; “Human milk polyunsaturated fatty acids are related to neurodevelopmental, anthropometric, and allergic outcomes in early life: a systematic review.” Mitguard S, Doucette O, Miklavcic JJ. Journal of Developmental Origins of Health and Disease. 2023;14(6): 763-772. DOI: 10.1017/S2040174423000454; “AA and DHA are decreased in paediatric AD/HD and inattention is ameliorated by increased plasma DHA.” Miklavcic JJ, Ivity E, MacDonald IM, Urichuk L, Mazurak VC, Rinaldi C, Clandinin MT. Human Nutrition & Metabolism. 2023; 31(200183). DOI: 10.1016/j.hnm.2022.200183.; “Potential effectiveness of Registered Dietitian Nutritionists in healthy behavior interventions for managing type 2 diabetes in older adults: a systematic review.” Dobrow L, Estrada I, Burkholder-Cooley N, Miklavcic JJ. Frontiers in Nutrition. 2022; 8(737410). DOI: 10.3389/fnut.2021.737410; “Ganglioside alters phospholipase trafficking, inhibits NF-kappaB assembly, and protects tight junction integrity.” Miklavcic JJ, Li Q, Skolnick J, Shoemaker GK, Thomson ABR, Mazurak VC, Clandinin MT. Frontiers in Nutrition. 2021; 8(705172). DOI: 10.3389/fnut.2021.705172; “Insights into novel infant milk formula bioactives.” Chou C, Skolnick J, Miklavcic JJ. Nutrition and Dietary Supplements. 2020; 12: 11-19. DOI: 10:2147/NDS.192099.; “Isolation and Characterization of Extracellular Vesicles in Human Milk.” Bickmore DC, Miklavcic JJ. Frontiers in Nutrition. 2020; 7(22). DOI:10.3389/fnut.2020.00022.; “Effectiveness of a community program for older adults with type 2 diabetes and multimorbidity: a pragmatic randomized controlled trial.” Miklavcic JJ, Fraser KD, Ploeg J, Markle-Reid M, Fisher K, Gafni A, Griffith LE, Hirst S, Sadowski CA, Thabane L, Triscott JAC, Upshur, R. BMC Geriatrics. 2020; 20(174). DOI: 10.1186/s12877-020-01557-0.; “Human breast milk feeding enhances the humoral and cell mediated immune response in a neonatal porcine model.” Miklavcic JJ, Badger TM, Bowlin AK, Matazel KS, Cleves MA, Leroith T, Saraf MK, Chintapalli SV, Piccolo BD, Shankar K, Yeruva L. The Journal of Nutrition. 2018; 148 (11): 1860-70. DOI: 10.1093/jn/nxy170.; “Community program improves quality of life and self-management in older adults with diabetes and multimorbidity.” Markle-Reid M, Ploeg J, Fraser K, Fisher K, Bartholomew A, Miklavcic JJ, Gafni A, Thabane L, Upshur R. Journal of the American Geriatrics Society. 2018; 66 (2): 263-273. DOI: 10.1111/jgs.15173.; “Ganglioside intake increases plasma ganglioside content in human participants.” Miklavcic JJ, Shoemaker GK, Schnabl KL, Larsen BMK, Thomson ABR, Mazurak VC, Clandinin MT. Journal of Parenteral and Enteral Nutrition. 2017; 41 (4): 657-666. DOI: 10.1177/0148607115620093.; “Fish oil mitigates myosteatosis and improves chemotherapy efficacy in a preclinical model of colon cancer.” Almasud AA, Giles KH, Miklavcic JJ, Baracos VE, Putman CT, Martins KJB, Mazurak VC. PLoS One. 2017; 12 (8): e0183576. DOI: 10.1371/journal.pone.0183576.; “Reduction of arachidonate in phospholipids is associated with increase in B cell activation marker in infants: a randomized trial.” Miklavcic JJ, Larsen BMK, Mazurak VC, Scalabrin DMF, MacDonald IM, Shoemaker GK, Casey L, VanAerde J, Clandinin MT. Journal of Pediatric Gastroenterology and Nutrition. 2017; 64 (3): 446-453. DOI: 10.1097/MPG.0000000000001283.; “Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease.” Miklavcic JJ, Hart T, Lees GM, Shoemaker GK, Schnabl KL, Larsen BMK, Bathe OF, Thomson ABR, Mazurak VC, Clandinin MT. World Journal of Gastroenterology. 2015; 21 (35): 10080-90. DOI: 10.3748/wjg.v21.i35.10080.

Dr John Miklavcic

Biography

Research Interests

Recent Creative, Scholarly Work and Publications

Faculty Directories by School or College