Dr. Susan Yang

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Recent Creative, Scholarly Work and Publications

Ye M., Nguyen S., Kim M.J., Hwang J.S., Bae G.W., Yang KH. and Shim I. Antidepressant Effect of Enzymatic Porcine Placenta Hydrolysate in Repeated Immobilization Stress-Induced Ovariectomized Female Mice. Curr. Issues Mol. Biol. 46, 6121–613 (2024). doi.org/10.3390/cimb46060366

Jayaprakash P, Isaev D, Yang KH. Beiram R, Oz M. Apigenin Alleviates Autistic-like Stereotyped Repetitive Behaviors and Mitigates Brain Oxidative Stress in Mice. Pharmaceuticals (Basel). Apr 9;17(4):482 (2024). doi: 10.3390/ph17040482

Isaev D, Yang KH, Oz M. Additive Effects of Citrus Juice Flavonoid Naringenin and Statins on HERG Channels Expressed in Xenopus Oocytes. Med Princ Pract. 2024 Apr 9;33(4):399-402 (2024). doi: 10.1159/000538780

Yang KH, Isaev D, Oz M. Additive Inhibition of HERG Channels Expressed in Xenopus Oocytes by Antipsychotic Drugs and Citrus Juice Flavonoid Naringenin. Pharmacology 2024 Sep 26:1-5 (2024). doi: 10.1159/000541005

Shabbir W, Yang KH, Dogar A M, Isaev D, Oz, M. (2023) Probing the ubiquitination-mediated function of Epithelial Sodium Channel in A549 cells. Current Molecular Pharmacology, 16(3): 411-418

Isaev D, Yang, K-H.S, Petroianu G, Lorke D.E, Oz, M. (2023) Methylene Blue Inhibits Cromakalim-Activated K+ Currents in Follicle-Enclosed Oocytes. Membranes, 13(2): 121

Oz M, King JR, Yang KS, Khushaish S, Tchugunova Y, Khajah MA, Luqmani YA, Kabbani N. (2023) a7 nicotinic acetylcholine receptor interaction with G proteins in breast cancer cell proliferation, motility, and calcium signaling. PLoS One. 18(7):e0289098

Oz, M., Keun-Hang, S.Y., Mahgoub, M., Petroianu, G. and Lorke, D.E. (2023) Effects of cannabidiol and other phytocannabinoids on voltage-and ligand-gated ion channels. Cannabis Use, Neurobiology, Psychology, and Treatment, Editors, Martin, C.R., Patel, V.B., Preedy, V.R., Elsevier-Academic Press, Oxford, U.K. Chapter 33, pp: 445-456

Isaev D, Yang KHS, Shabbir W. Howarth FC, and Oz M (2022) Capsaicin Inhibits Multiple Voltage-Gated Ion Channels in Rabbit Ventricular Cardiomyocytes in TRPV1-Independent Manner. Pharmaceuticals

Shabbir W. Yang KHS, Dogar AM, Isaev D, and Oz M (2022) Probing the ubiquitination-mediated function of Epithelial Sodium Channel in A549 cells. Curr Mol Pharmacol

Oz M, Yang KHS, and Mahgoub MO (2022) Effect of cannabinoids on ligand-gated ion channels. Frontiers in Physiology

Shenyue Jia, Seung Hee Kim, Son V. Nghiem, KHS Yang, Menas C. Kafatos, (2020) Investigating the Lagged Relationship between SMAP Soil Moisture and Live Fuel Moisture in California, USA. In IGARSS 2020-2020 IEEE International Geoscience and Remote Sensing Symposium, 4485-4488

El Neibrish E, Alzaabi AH, Howarth L, Lorke DE, Yang KHS, Howarth FC, and Oz, M (2021) Noncompetitive Actions of Capsaicin on Ligand-Gated Ion Channels. 25th Health Science Centre Poster Conference P:17

Shabbir W, Yang KHS, Sadek B, and Oz M (2021) Apigenin and Structurally Related Flavonoids Allosterically Potentiate the Function of Human a7-Nicotinic Acetylcholine Receptors Expressed in SH-EP1 Cells. Cells Volume Issue 5

Eslam El Nebrisi, Dietrich E. Lorke, Luke Howarth, Asma H. Alzaabi, Yang KHS, Frank C. Howarth, Murat Oz (2020) Capsaicin is a negative allosteric modulator of the 5-HT3 receptor. Frontiers in Pharmacology, Frontiers in Pharmacology 31 August 2020 doi.org/10.3389/fphar.2020.01274.

Shenyue Jia, Seung Hee Kim, Son V. Nghiem, Keun Hang S. Yang, Menas Kafatos (2020), Investigating the Lagged Relationship between Smap Soil Moisture and Live Fuel Moisture in California, USA, 2020 IEEE International Geoscience and Remote Sensing Symposium

Alzaabia AH, Howartha L, Nebrisia EE, Syeda N, Yang KH, Howarthc FC, Oz M (2019) Capsaicin inhibits the function of a7-nicotinic acetylcholine receptors expressed in Xenopus oocytes and rat hippocampal neurons. European Journal of Pharmacology 857:172411.

Kafatos, M.C., Yang, K-H S (2018) The Participating Mind in the Quantum Universe, Cosmos and History: The Journal of Natural and Social Philosophy 14(1): 40-55.

Yang, K-H S, Kafatos, M.C. (2018) Geometroneurodynamics and Neuroscience. Cosmos and History: The Journal of Natural and Social Philosophy, vol. 14, no. 2.

El Nebrisi EG, Bagdas D, Toma W, Al Samri H, Brodzik A, Alkhlaif Y, Yang KH, Howarth FC, Damaj IM, Oz M (2018) . Curcumin Acts as a Positive Allosteric Modulator of a7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain. J. Pharmacol. Exp. Ther. 365(1):190-200.

El Nebrisi E, Yang KH, Howarth F, Kabbani N, Oz M, Curcumin potentiates the function of human a7-nicotinic acetylcholine receptors expressed in SH-EP1 cells. In Preparation.

Gaber E Nebrisi E, Bagdas D, Toma W, Brodzik A, Alkhlaif Y, Yang KH, Howarth CF, Damaj MI, Oz M. (2017) Curcumin acts as a positive allosteric modulator of a7-nicotinic acetylcholine receptors and reverses nociception in mouse models of inflammatory and neuropathic pain. Submitted to Eur J Pharmacol.

Sultan A, Yang KH, Isaev D, Nebrisi EE, Syed N, Khan N, Howarth CF, Sadek B, Oz M. (June 2017) Thujone inhibits the function of a7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm. Toxicology. 1;384:23-32.

Oz M, El Nebrisi EG, Yang KH, Howarth FC, Al Kury LT. (July 2017) Cellular and Molecular Targets of Menthol Actions. Front Pharmacol. 8:472.

Al Zaabi A.H., Yang KH., Sadek B., Howarth C.F., Oz M. (2016) Effects of Capsaicin on the Function of a7-Nicotinic Acetylcholine Receptors. In preparation.

Sultan A., Lozon Y., Yang KH., Syed N, Sadek B., Howarth C.F., Oz M. (2016) Effects of Thujone on the Function of a7-Nicotinic Acetylcholine Receptors. Submitted to Toxicology

Menas Kafatos, KeunHang Susan Yang (2016) The Quantum Universe: the Philosophical Foundations and Oriental Medicine. Integrative Medicine Research, Elsevier 5:237-243

Lozon Y, Sultan A, Lansdell SJ, Prytkova T, Sadek B, Yang KH, Howarth FC, Millar NS, Oz M. (2016) Inhibition of Human a7 Nicotinic Acetylcholine Receptors by Cyclic Monoterpene Carveol. Eur J Pharmacol. 776: 44-51.

Yang Keun-Hang, Syed M. Nurulain, Frank C. Howart, Murat Oz (2015), CURCUMIN POTENTIATES HUMAN ?7-NICOTINIC ACETYLCHOLINE RECEPTORS, SFN*2015(Suppl.)

Andreas Schilbach, Tatiana Prytkova, Keun-Hang Yang (2015), The Effect of gamma9-Tetrahydrocannabinol, Cannabidiol, Menthol and Propofol on 5-Hydroxytryptamine Type 3 Receptors—A Computational Approach, Computational Neuroscience Meeting, CNS*15 (Suppl.).

Sadek B, Khanian SS, Ashoor A, Prytkova T, Ghattas MA, Atatreh N, Nurulain SM, Yang KH, Howarth FC, Oz M. (2015) Effects of antihistamines on the function of human a7-nicotinic acetylcholine receptors. Eur J Pharmacol. 746:308-316.

Ali RM, Al Kury LT, Yang KH, Qureshi A, Rajesh M, Galadari S, Shuba YM, Howarth FC, Oz M. (2015) Effects of cannabidiol on contractions and calcium signaling in rat ventricular myocytes. Cell Calcium. 57: 290-299.

Murat Oz, Yosra Lozon, Ahmed Sultan, Keun-Hang Susan Yang, Sehamuddin Galadari (2015) Effects of Monoterpenes in Ion Channels of Excitable Cells, Pharmacology and Therapeutics, 152:83-97.

Nurulain S, Prytkova T, Sultan AM, Ievglevskyi O, Lorke D, Yang KH, Petroianu G, Howarth FC, Kabbani N, Oz M. (2015) Inhibitory actions of bisabolol on a7-nicotinic acetylcholine receptors. Neuroscience. 306: 91-99.

Al Kury LT, Yang KH, Thayyullathil FT, Rajesh M, Ali RM, Shuba YM, Howarth FC, Galadari S, Oz M. (2014) Effects of endogenous cannabinoid anandamide on cardiac Na+/Ca2+ exchanger. Cell Calcium. 55: 231-237.

Al Kury LT, Voitychuk OI, Ali RM, Galadari S, Yang KH, Howarth FC, Shuba YM, Oz M. (2014) Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes. Cell Calcium. 55:104-118.

Al Kury LT, Voitychuk OI, Ali RM, Galadari S, Yang KH, Howarth FC, Shuba YM, Oz M (2014), Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes, Cell Calcium. 2014 Feb;55(2):104-18. doi: 10.1016/j.ceca.2013.12.005. Epub 2014 Jan 5.

Oz M, Al Kury L, Yang KH, Mahgoub M, Galadari S (2014), Cellular approaches to the interaction between cannabinoid receptor ligands and nicotinic acetylcholine receptors, Eur J Pharmacol. 2014 May 15;731:100-5. doi: 10.1016/j.ejphar.2014.03.010. Epub 2014 Mar 16.

Al Kury LT, Yang KH, Thayyullathil FT, Rajesh M, Ali RM, Shuba YM, Howarth FC, Galadari S, Oz M (2014), Effects of endogenous cannabinoid anandamide on cardiac Na?/Ca²? exchanger, Cell Calcium. 2014 May;55(5):231-7. doi: 10.1016/j.ceca.2014.02.017. Epub 2014 Mar 11.

Al Kury LT, Voitychuk OI, Yang, KH, Thayyullathil FT, Doroshenko P, Ramez AM, Shuba YM, Galadari S, Howarth FC, Oz M (2014), Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes, Br J Pharmacol. 2014 Jul;171(14):3485-98. doi: 10.1111/bph.12734.

Jacob C. Nordman; Daniel Veltri; Keun-Hang Yang; Lina Al Kury; Yaroslav Shuba; Mohamed Mahgoub; Frank C. Howarth; Bassem Sadek; Amarda Shehu; Nadine Kabbani; Murat Oz (2013), Menthol binding and inhibition of a7-nicotinic acetylcholine receptors, PLOS ONE, 2013 Jul 23;8(7):e67674. doi: 10.1371/journal.pone.0067674.

Mohamed Mahgoub, Keun-Hang Yang , Abrar Ashoor, Nadine Kabbani, Lina Al Kury, Bassem Sadek, Christopher Howarth, Sehamuddin Galadari, Murat Oz (2013), Effects of cannabidiol on the function of & a 7-nicotinic acetylcholine receptors, Journal of Pharmacology and Experimental Therapeutic, 2013 Nov 15;720(1-3):310-9. doi: 10.1016/j.ejphar.2013.10.011. Epub 2013 Oct 18.

Oz M, Lorke DE, Yang Keun-Hang, Petroianu G(2013), On the interaction of ß-amyloid peptides and a7-nicotinic acetylcholine receptors in Alzheimer disease. Curr. Alzheimer Res. 10: 618-630.

Ashoor A, Nordman J.C., Veltri D., Yang Keun-Hang, Shuba Y., Al Kury L., Sadek B., Howarth FC, Shehu A., Kabbani N., Oz M. (2013), Menthol inhibits 5-HT3 receptor-mediated currents J Pharmacol Exp Ther., , doi:10.1124/jpet.113.203976.

Yang Keun-Hang, D. Lorke, A. Ashoor, S. M. Nurulain, C. F. Howarth, N. Kabbani, M. Oz (2013), Menthol inhibition of human serotonin type 3 receptors expressed in xenopus oocytes, SFN*2013(Suppl.)

K.-H. S. YANG, M. MAHGOUP, A. ASHOOR, C. F. HOWARTH, S. GALADARI, M. OZ (2012), Effects of cannabidiol on human a7-nicotinic acetylcholine receptors, SFN*2012(Suppl.)

Al Mansouri AS, Al Mansouri AS, Lorke DE, Nurulain SM, Ashor A, Yang Keun-Hang, Petroianu G, Isaev D, Oz M (2012), Methylene Blue Inhibits the Function of a7-Nicotinic Acetylcholine Receptors, CNS Neurolo Disord Drug Targets, 11:791-800.

Abrar Ashoor, Dietrich E. Lorke, Syed M. Nurulain, Lina Al Kury, Georg Petroianu, Yang Keun-Hang, and Oz Murat. (2011), “Effects of Phenothiazine Class Antipsychotics on the Funtion of alpha7-Nocptomoc Acetylcholine Receptors”, European Journal of Pharmacology, 673 (Issues 1-3):25-32.

Yang Keun-Hang, D. Isaev, M. Morales, G. Petroianu, S. Galadari, Oz M. (2010), “The effect of ?9-tetrahydrocannabinol on 5-HT3 receptors depends on the current density”, Neuroscience, 171:41-49.

Yang Keun-Hang, Sehamuddin Galadari, Marisela Morales, Toni S. Shippenberg, and Oz Murat(2010), “The Nonpsychoactive Cannabinoid Cannabidiol Inhibits Human 5-HT3 Receptor-Mediated Currents in Xenopus Oocytes”, Journal of Pharmacology and Experimental Therapeutic, 333:547-554.

Prasad Anuup. K., Yang Keun-Hang, El-Askary Hesham. Menas., Kafatos M (2009) "Melting of major Glaciers in the western Himalayas: evidence of climatic changes from long term MSU derived tropospheric temperature trend (1979 - 2008)", Ann. Geophys.

Oz Murat, Yang Keun-Hang, Renaud Leo P, O’Donovan Michael J. (2007) Cholecystokinin B type receptors mediate a G protein-dependent depolarizing action of cholecystokinin (CCK-8s) on rodent neonatal spinal ventral horn neurons. Journal of Neurophysiology, 98(3):1108-14.

Oz Murat, Yang Keun-Hang, Dinc M, Shippenberg TS. (2007) The Endogenous Cannabinoid Anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed xenopus oocytes. Journal of Pharmacology and Experimental Therapeutics, 323(2):547-54.