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- Research Center: Structural Biology Research Center
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- Research at the School of Pharmacy
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- Recent Awards & Articles
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»Center for Targeted Drug Delivery Structural Biology Research Center (SBRC)
Partnership Interest Form
The Center for Targeted Drug Delivery (CTDD) is seeking academic, industry and international partners for collaboration in our dynamic, innovative research.
For more information on this exciting opportunity with Chapman's CTTD, please fill out this form »
Structural Biology Research Center (SBRC)
The Structural Biology Research Center (SBRC) is housed by the Chapman University School of Pharmacy (CUSP) in the Harry and Diane Rinker Health Science Campus, Irvine. The center offers expertise and access to cutting-edge instrumentation for biomolecular structural analysis and drug development, including x-ray crystallography, NMR spectroscopy, and protein-ligand interaction analysis.
Our mission at SBRC is to advance structure-based drug design and development by integrating of structural and biophysical techniques for the characterization of the structure and function of biomolecules and macromolecular complexes. To accomplish this mission, we aim to develop collaborations and partnerships with other academic institutions as well as Biotech and pharmaceutical companies.
Center Activities:
SBRC provides training, access to the equipment, and any needed assistance in sample preparation, as well as X-ray diffraction, NMR, and SPR data collection and analysis.
SBRC Members:
- Dr. Innokentiy Maslennikov - NMR Spectroscopy
- Dr. Miao Zhang - X-ray Crystallography
- Dr. Gennady Verkhivker - Computational Biology
Equipment
X-Ray Crystallography
Mosquito Crystallization Robot (TTP Labtech. Inc)
- High-throughput crystallization of biomacromolecules (soluble and membrane proteins, peptides)
D8 Venture Liquid Gallium Metaljet (Bruker)
- X-ray diffraction data collection
- X-ray diffraction data analysis and structure determination
Stereo Microscope
Nuclear Magnetic Resonance (NMR)
Avance III HD 400 MHz (Bruker)
- Solution NMR spectroscopy data collection (1H, 13C, 15N, 19F, 31P, etc.)
- Small Molecule/Protein Characterization
- Label-free detection of ligand-target interactions
Protein-Ligand Interaction Assay
Biacore S200 (GE Healthcare)
- Surface Plasmon Resonance (SPR)
- Label-free detection of protein-protein or protein-ligand interactions
SBRC Pricing
- Research
- Form Thank You
- Center for Targeted Drug Delivery Partnership Interest Form
- Research Centers
- Research Center: Structural Biology Research Center
- Research Facilities
- Post Doctoral Fellows & Research Associates
- Research at the School of Pharmacy
- Center for Patient Safety Research and Education
- Recent Awards & Articles
- Research Center: Targeted Drug Delivery
- Student Research Opportunities
- Women in AIWidget